Tenovate Cream 0.05%
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Tenovate Cream 0.05%


Tenovate Cream 0.05% is used in the treatment of different skin conditions including rash, psoriasis, allergy, and others. Clobetasol is the active ingredient of this medication.

2 Tubes $11.00
8 Tubes $40.00
16 Tubes $72.00

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This cream is often used to treat a wide variety of skin conditions (such as rash, allergies, dermatitis, eczema, psoriasis, and others). Doctors may also prescribe Tenovate Cream 0.05% to treat other conditions not listed in this document. While the active ingredient is Clobetasol propionate, it also contains other inactive ingredients such as propylene glycol, sodium hydroxide, purified water, mineral oil, and others. Tenovate Cream 0.05% belongs to the class of medicines called corticosteroids. This medication also helps to reduce skin irritation, redness, itching, swelling, and others. These symptoms may occur during skin conditions listed in this article.

The manufacturer of Tenovate Cream 0.05% is GlaxoSmithKline.

How to Use Tenovate Cream 0.05%?

Using this cream 1-2 times per day is usually the recommended dose or as directed by your healthcare professional. In case you do not notice the desired result, your doctor may gradually increase the dosage for several weeks. However, do not use Tenovate Cream 0.05% more often than is prescribed by the doctor because it will not treat your condition faster. To get the most benefit from Tenovate Cream 0.05%, you should use it at a fixed time every day.

  • Before using, wash and dry your hands and the affected area.
  • Afterward, apply a thin layer of cream and gently rub it in.
  • It is not allowed to cover the area with bandages or others.
  • You should also wash your hands after using this will help to avoid touching cream with your eyes, mouth, or nose. However, if you get this medicine in the areas listed above, rinse with a large amount of water.

In case your condition does not improve in the first 2 weeks of treatment, contact your healthcare professional immediately.


Dosages fluctuate among patients because it depends on your age, response to treatment, other medications that you may be using, and the severity of your condition. If you are not sure what dosage is better for you, avoid using this medicine or consult a doctor.

  • Tenovate Cream 0.05% (30 g/tube)

Missed Dose

However, it is not advised to miss a dose because symptoms may return and it may result in a return of the symptoms. Therefore, your medical condition may become worse or more difficult to treat. In any case, if you miss one, you should administer the dose as soon as possible. If it is almost time for the next dose, just skip the missed dose and continue the regular treatment as prescribed. It is not allowed to use the next time an increased dose of Clobetasol because it may increase your risk of severe adverse effects.


If you are using Tenovate Cream 0.05% more often than is prescribed by your doctor, you may experience an overdose. Symptoms of overdose include passing out, severe dizziness, trouble breathing, slow or irregular heartbeat, and others. In case you are experiencing any of the symptoms listed above, you should interrupt using this medicine and get medical help immediately. Ask your healthcare professional if you have any other questions.

Side Effects of Tenovate Cream 0.05%

You may notice certain side effects while using this medicine. Some factors that can provoke side effects are overdose and dehydration. There are three types of side effects such as mild, moderate, and severe.

Mild Side Effects

Usually, patients ignore this category of side effects but it is advised to inform your doctor if you experience any of them. Check some examples below:

  • Dryness or redness at the application site
  • Skin thinning
  • Stretch marks

Moderate Side Effects

This category of side effects usually is not dangerous for the patients and they can safely keep using this medicine. For example:

  • Itching
  • Skin discoloration
  • Folliculitis (small red bumps on the skin)

Severe Side Effects

The following side effects usually are rare. However, if you notice any of them, stop using this cream and immediately consult a doctor. In addition, your doctor may be able to help you to avoid or prevent side effects. Check below some examples:

  • Skin atrophy
  • Skin burning or stinging
  • Acne
  • Extreme hair growth

This medicine may be absorbed from the skin into the bloodstream in children or in adults who are using Tenovate Cream 0.05% for long periods. Thus, you may experience certain symptoms such as weight loss, headaches, increased urination or thirst, vision problems, and others. Talk with your doctor for more details.

Consult a doctor immediately if you are experiencing any of the adverse reactions listed above or both of them at the same time.

Drug Interaction

Some medications may interact with Tenovate Cream 0.05% and change how Clobetasol works. It means that other drugs may reduce the effectiveness of the drug or even increase the risk of adverse effects. Hence, before using Tenovate Cream 0.05%, it is advised to share a list of products that you are using with your doctor. Examples include herbal products, vitamins, supplements, prescription medicines, nonprescription medicines, and others. Check some examples below:

  • Prednisone
  • Cyclosporine
  • Amlodipine
  • Aspirin
  • Acarbose
  • Amphotericin B
  • Metformin
  • Insulin
  • Glyburide
  • Chlorpropamide

This article does not contain a full list of drug interactions. That’s why it is important to talk with a doctor before using this medication.


Before using this medicine, you should tell your physician if you are allergic to the ingredients of the drug or if you have any other allergies. However, you should share your medical history with your doctor. Examples include:

  • Ocular toxicities
  • Infections
  • Hyperadrenocorticism
  • Diaper rash
  • Diabetes
  • Immune system problems
  • Poor blood circulation
  • Skin conditions (such as perioral dermatitis, rosacea, and others)

This medicine may be used during pregnancy with a doctor’s prescription only. Otherwise, it may harm you and your unborn baby. There is no information if Clobetasol passes into breast milk or not. Therefore, consult a doctor before breastfeeding.

If this medicine is used in children for long periods, it may temporarily slow down a child’s growth. Check regularly your child’s height.


  • It is advised to store this medicine at room temperature and away from direct sunlight and moisture. Thus, you should not keep Tenovate Cream 0.05% in the bathroom.
  • Keep away Clobetasol from the reach of children and pets because it may be harmful to them.

Additional information

Active Ingredient





1 tube/pack




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