Leetrexate 2.5 mg
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Leetrexate 2.5 mg


Leetrexate 2.5 mg contains Methotrexate as an active ingredient. This medication is used to treat a wide variety of cancers. Do not use it without a doctor’s approval.

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A medicine that is used in treating severe psoriasis and a wide variety of cancers. Physicians may also prescribe this medicine to treat other medical conditions not listed in this document. While the active ingredient is Methotrexate, it also contains other inactive ingredients such as lactose, pregelatinized starch, magnesium stearate, and others. Leetrexate 2.5 mg belongs to the class of medications called antimetabolites. In any case, it is not recommended to use this medicine without the doctor’s approval because it may lead to unwanted results.

The manufacturer of Leetrexate 2.5 mg is Johnlee Pharmaceuticals Pvt. Ltd.

How to Administer Leetrexate 2.5 mg?

Take the pill whole by mouth with or without food. To swallow the tablet use a glass of water and avoid other beverages such as alcohol because it may increase your risk of adverse effects. Do not break, crush, or chew the tablet while swallowing because you may have a bitter taste in your mouth. In case you notice stomach upset or nausea, you can administer this medicine with milk or light food. In addition, do not use Leetrexate 2.5 mg more than is allowed because it will not treat your health condition faster. Your doctor may adjust the dosage in case you do not notice the desired result. To get a better effect from this medication, you should follow the doctor’s recommendations carefully such as administering the pill each day and at the same time.

Using the liquid form of this medicine requires a special measuring spoon or device. Otherwise, you may get the wrong dose, which may also increase your risk of adverse effects. If you see no improvements in your condition in the first month of treatment, discuss it with your doctor right away.


The dosages usually are based on your age, the severity of the health condition, other medications that you may be using, weight, and your response to treatment. If you have doubts about what dosage is better for you, talk to a doctor. Additionally, keep taking Leetrexate 2.5 mg even if you feel well because if you stop the treatment suddenly without a doctor’s approval, symptoms may return.

  • Leetrexate 2.5 mg

Missed Dose: If you forget to administer this medication, doctors usually recommend taking the tablet as soon as you remember about it. In any case, if it is too close to the time for the next dose, just skip the missed dose and continue the regular treatment. It is not recommended to administer the next time an increased dose to catch up because it may increase the risk of negative effects.

Overdose: You may experience an overdose due to an increased dose of Methotrexate. Symptoms of overdose include severe dizziness, passing out, shortness of breath, fast or pounding heartbeat, and others. In case you are noticing any of the symptoms listed above, stop taking Leetrexate 2.5 mg and get medical help right away. Ask your doctor in case you have any questions.

Adverse Effects of Leetrexate 2.5 mg

Methotrexate like other medications may give you some side effects. If you are on treatment with this drug, you may not experience any of the following adverse reactions. Dehydration, overdose, and allergy are some factors that can provoke side effects.

Common Adverse Effects

It is not recommended to ignore the following adverse effects. In any case, inform your physician about all the side effects that you are experiencing. Examples include:

  • Nausea
  • Dry mouth
  • Headaches
  • Flatulence (gas)
  • Diarrhea
  • Constipation
  • Dizziness

Severe Adverse Effects

In rare cases, this category of side effects may occur. Therefore, if you notice any of the following negative effects, it is recommended to stop taking this medicine and consult a doctor at once. In addition, your physician may help you to prevent or avoid negative effects. Check some examples below:

  • Abdominal pain
  • Muscle spasms
  • Irregular heartbeat
  • Seizures
  • Joint pain
  • Stomach cramping or pain
  • Bloody stools
  • Sore tongue

This document does not contain a complete list of side effects. Tell your doctor if you are experiencing any of the adverse reactions listed above or any other effects.


  • It is recommended to store this medication at room temperature (below 30 Celsius degrees) and away from moisture and direct sunlight. Thus, it is not allowed to keep Leetrexate 2.5 mg in the bathroom.
  • Keep away Methotrexate from the reach of children and pets because it may be harmful to them.


There are some substances and medications that may interact with Methotrexate and reduce the effectiveness of the medicine or even increase your risk of negative effects. Hence, you should tell your physician about all products that you are using before taking Leetrexate 2.5 mg. Examples include prescription drugs, nonprescription drugs, herbal products, supplements, vitamins, and others. Check some examples of drug interaction below:

  • Warfarin
  • Rifampin
  • St John’s wort
  • Other medicines that contain Methotrexate as an active ingredient
  • Alcohol
  • Mavacamten
  • Clopidogrel
  • Cilostazol
  • Rilpivirine
  • Ketoconazole
  • Atanazavir
  • Omeprazole
  • Aspirin
  • Levothyroxine
  • Duloxetine
  • Cyanocobalamin

Leetrexate 2.5 mg may also interact with certain diseases. For example:

  • Hypomagnesemia
  • Bone fractures
  • Liver disease
  • C. Diff

This article does not contain all possible drug and disease interactions. That’s why you should consult a doctor before taking this medication. Moreover, you should not start, stop, or change the dosages without the doctor’s approval because you may experience unwanted results.


Share your medical history with your physician before taking this drug. Especially, if you are allergic to the ingredients of the drug or if you have any other allergies. Examples include:

  • Liver disease (such as cirrhosis)
  • Lupus
  • Osteoporosis (bone loss)
  • Abuse of alcohol
  • Cancer
  • Surgery
  • Diabetes
  • Bleeding problems

Methotrexate may affect your vision (such as blurred vision) or may make you drowsy or dizzy. Therefore, you should avoid or limit alcoholic drinks while you are on treatment with this medicine because these effects may increase. Moreover, until you feel better, you should not drive or operate machinery because it may be harmful to you.

During pregnancy, you should use Leetrexate 2.5 mg with a doctor’s approval only. Otherwise, it may harm your unborn baby. Additionally, it is advised to consult a doctor before breastfeeding because it is not known if this medication passes into breast milk. However, similar medications pass into breast milk. Talk to a doctor for further information.

Additional information

Active Ingredient



Johnlee Pharmaceuticals Pvt. Ltd.


10 tabs/blister




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