This medicine is usually used in patients who are suffering from colon and rectum cancer. However, physicians may also prescribe this medicine to treat certain cancers of the digestive system (gastrointestinal stromal tumor) and other diseases not listed in this article. Regonat 40 mg belongs to a group of medicines called kinase inhibitors. Regonat 40 mg contains Regorafenib as an active ingredient. Nonetheless, it also contains other inactive ingredients such as magnesium stearate, povidone, colloidal silicon dioxide, microcrystalline cellulose, and others. You should not use this product without the physician’s prescription because it may lead to unwanted results.
The manufacturer of Regonat 40 mg is Natco Pharma Limited.
How to Use Regonat 40 mg?
One cycle of treatment is taking one tablet daily for 21 days and then interrupting the treatment for one week. Continue using this medicine as directed by your healthcare provider. Use a glass of water to administer this medication and avoid other beverages such as alcohol or grapefruit juice because your risk of adverse effects may increase. While swallowing, it is not advised to crush, chew, or slip the tablet. If stomach upset or nausea occurs, you can administer the pill with a low-fat meal or milk.
Do not use Regonat 40 mg more often than is allowed because your condition will not improve faster. In some cases, your doctor may gradually increase the dosage for several weeks or even change the brand of the medication.
Measure carefully the dose with a special spoon or cup if you intend to use the liquid form of Regonat 40 mg. Otherwise, using a household teaspoon, you may get the wrong dose, which may also increase your risk of negative effects. Tell your healthcare provider if your condition does not improve or if it worsens.
Dosages
Commonly, the dosages are based on the severity of the condition, other drugs you may use, response to therapy, and age. Do not use this medicine if you are not sure what dosage is better for you or consult a doctor. In addition, you should not interrupt the treatment too early because symptoms may return. Therefore, your condition may become worse or more difficult to treat.
- Regonat 40 mg
Missed Dose
In case you forget about this medicine, doctors recommend taking the dose as soon as you remember. In any case, if it is almost time for the next dose, just skip the missed dose and continue the regular treatment as prescribed. Do not administer a double dose at the same time because you may experience severe side effects.
Overdose
If you are administering more tablets than is prescribed by a doctor, you may notice an overdose. Symptoms of overdose include severe dizziness, passing out, irregular heartbeat, breathing problems, and others. In case you experience any of the symptoms listed above, stop using this medicine and consult a doctor at once. Discuss with a healthcare provider for more details.
Adverse Effects of Regonat 40 mg
Regonat 40 mg may give you some side effects during treatment but if your body adjusts to Regorafenib, any of the following adverse effects may disappear. Some factors that can provoke adverse reactions are dehydration, overdose, and allergy.
Common Adverse Effects
This category of adverse effects usually is not dangerous for the patients and they can continue the treatment safely. In addition, your healthcare professional may be able to help you to prevent or avoid side effects. Check some examples below:
- Rash
- Diarrhea
- Vomiting
- Weakness
- Poor appetite
- Voice changes
- Nausea
Severe Adverse Effects
This category of side effects may occur in rare cases due to an increased dose of Regorafenib. However, stop using this medicine and get medical help right away, if any of the following adverse effects occur. Examples include:
- Fever
- Infection
- Low blood platelets
- Anemia (low amount of red blood cells)
- Pain
- Hypertension
- Inflammation of the mouth
- Weight loss
- Bilirubin in urine
- Increased liver enzymes
Consult with a doctor right away if you experience any of the adverse reactions listed above or both of them at the same time.
Interactions
Regorafenib may interact with some drugs and increase your risk of side effects or decrease the effectiveness of Regonat 40 mg. That’s why you should tell your doctor about all products that you are using before administering this medication. Examples include herbal products, vitamins, supplements, prescription medicines, nonprescription medicines, and others. Check some drug interactions below:
- Warfarin
- Ibuprofen
- Clopidogrel
- Irinotecan
- Aspirin
- Nefazodone
- Rifampin
- Clarithromycin
- Rifabutin
- Nelfinavir
- Phenytoin
- Ketoconazole
- Itraconazole
- Ritonavir
- St. John’s Wort
- Telithromycin
- Heparin
- Teriflunomide
- Rivaroxaban
- Piroxicam
- Naproxen
- Mefenamic acid
- Lomitapide
- Ketorolac
- Indomethacin
- Diclofenac
- Apixaban
Discuss with a healthcare provider before using this medicine because this document does not contain all possible drug interactions. Furthermore, you should not start, stop, or change the dosages without the doctor’s approval because you may experience unwanted results.
Precautions
Tell your physician if you have an allergy to the ingredients of the drug or if you have any other allergies. Share your medical history with your doctor before taking Regorafenib. Examples include:
- Lung toxicity
- Liver problems
- High blood pressure (hypertension)
- Heart disease (such as chest pain, heart failure, and others)
- Bleeding problems
- Blood vessel problems (such as aneurysm)
- Recent major surgery or injury
Do not use this medicine during pregnancy without the doctor’s prescription because it may harm you and your unborn baby. Moreover, you should talk with a doctor before breastfeeding because it is not known if this medicine passes into breast milk.
Where to Buy Regonat 40 mg?
You can find this medicine at many local pharmacy stores. However, you can choose the online pharmacy BrandRx.to. We guarantee 100% original branded medicines, low cost compared to pharmacy stores near your house, fast delivery, as well as great customer support. In case you do not get the correct medications, you can return or change them. Additionally, on BrandRx.to you can find drugs used to treat other diseases such as osteoporosis, lung disease, erectile dysfunction (ED), heart disease, mental disorders (such as depression), bacterial, fungal, or viral infections, and other conditions. Place the order on our website and we will bring the medicines right to your place.
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