Aldactone 25 mg
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Aldactone 25 mg


Aldactone 25 mg is usually used to treat heart failure and hypertension. Healthcare providers may prescribe this medication to treat kidney or liver disease. The active ingredient of this medicine is Spironolactone.

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Aldactone 25 mg is used in patients who are suffering from hypertension (high blood pressure). Doctors may also prescribe this medicine to prevent angina (heart-related chest pain) and treat other conditions not listed in this article. It works by decreasing blood pressure, which helps lower the heart’s workload. This helps to prevent heart attacks and strokes. Aldactone 25 mg contains Spironolactone as an active ingredient. Nonetheless, it also contains other inactive ingredients such as sodium starch glycolate, magnesium stearate, microcrystalline cellulose, and others. Aldactone 25 mg is known as a calcium channel blocker drug. In any case, if an attack of chest pain occurs, you can use sublingual nitroglycerin to relieve angina as directed by your doctor.

The manufacturer of Aldactone 25 mg is RPG Life Sciences Ltd.

How to Use Aldactone 25 mg?

One tablet daily is usually considered the recommended dose or as your healthcare professional directs. Take the tablet whole by mouth with or without food. Do not split, chew, or break the pill while swallowing because you may notice an unpleasant taste in your mouth. Use a glass of water to administer this medicine and avoid other alcoholic beverages because your risk of severe side effects may increase. If you notice nausea or stomach upset, you can administer the tablet with milk or light food. To get a better effect from Aldactone 25 mg, you should administer this drug each day and at the same time.

Using this product more frequently than is allowed, will not treat your condition faster. In case you are not noticing the desired result, your doctor may gradually increase the dosage for several weeks.

If you prefer the liquid form of this medicine, measure carefully the dose with a special measuring cup or spoon. It is not allowed to use a household teaspoon because you may not get the correct dose. If you see no improvements in your condition in the first week of treatment, contact a physician immediately.


The dosages fluctuate among patients because it depends on the severity of the condition, other medicines you may use, age, and response to therapy. Do not take Aldactone 25 mg if you are not sure what dosage is better for you or consult a doctor. Furthermore, you should not stop the treatment suddenly without the physician’s approval because symptoms may return. Thus, your condition may become difficult to treat.

Missed Dose

In case you forget about this medicine, physicians recommend administering the dose as soon as you remember. In any case, if it is approaching the time for the next dose, simply skip the missed dose and continue the regular treatment as prescribed. Do not take a double dose the next time to make up because you may experience severe side effects.


If you take more tablets than is allowed by your doctor, you may notice an overdose. Symptoms of overdose include irregular heartbeat, shortness of breath, severe dizziness, fainting, and others. If you experience any of the symptoms listed above, interrupt using this product and seek medical attention right away. Discuss with your healthcare provider for more details.

Adverse Effects of Aldactone 25 mg

All medications may give you certain side effects during treatment and Aldactone 25 mg is not an exception. However, any of the following negative effects may disappear if your body adjusts to Spironolactone. There are some factors that can provoke side effects such as dehydration, overdose, and allergy.

Common Adverse Effects

Patients usually, can continue safely using Aldactone 25 mg even if they experience any of the following negative effects. Furthermore, your physician may help you to prevent or avoid side effects. Check some examples below:

  • Dizziness
  • Lightheadedness
  • Flushing
  • Nausea
  • Headaches
  • Fatigue
  • Sleepiness

Severe Adverse Effects

Rarely, this category of side effects may occur usually due to an increased dose of Spironolactone. Stop using this product and get medical help right away if any of the following side effects appear. Examples include:

  • Abdominal pain
  • Swelling of the ankles or feet
  • Fainting
  • Irregular heartbeat
  • Unusual sweating

Talk to a doctor if you notice any of the adverse reactions listed above or both of them at the same time.


Aldactone 25 mg may interact with some drugs and substances. It means that other medicines may change how Spironolactone works by reducing its effectiveness or even increasing the risk of adverse effects. That’s why you should share a list of products that you are using with your doctor before administering Spironolactone. Examples include prescription medicines, nonprescription medicines, supplements, vitamins, herbal products, and others. Check below some examples of drug interaction:

  • Zolpidem
  • Vericiguat
  • Verapamil
  • Ziprasidone
  • Erectile dysfunction or pulmonary hypertension medicines (such as Vardenafil, Avanafil, Sildenafil Citrate, and others)
  • Tyropanoate
  • Thioridazine
  • Thalidomide
  • Tizanidine
  • Tacrolimus
  • Succinylcholine
  • St. John’s Wort
  • Siponimod
  • Simvastatin
  • Selegiline
  • Safinamide
  • Rifabutin
  • Ritonavir
  • Rifampin
  • Rifapentine
  • Quetiapine
  • Primidone
  • Phenobarbital
  • Phenytoin
  • Opium
  • Nitroglycerin
  • Nortriptyline
  • Nevirapine
  • Mitotane
  • Meloxicam
  • Methadone
  • Morphine
  • Itraconazole
  • Fosphenytoin
  • Enzalutamide
  • Dolasetron
  • Ceritinib
  • Carbamazepine
  • Apalutamide

Talk to a doctor before taking Aldactone 25 mg because this article does not contain all possible drug interactions. In addition, it is not advised to start, stop, or change the dosages without the doctor’s approval because you may experience unwanted results.


Do not use this medicine if any of the following cases occur. Examples include:

  • Allergy to the ingredients of the drug or any other allergies
  • Liver and kidney disease
  • Heart disease (coronary arterial disease, heart failure, and others)
  • Cardiogenic shock
  • Hypotension (low blood pressure)
  • Diabetes
  • Cancer
  • Surgery

Spironolactone may make you drowsy or dizzy. Limit or avoid alcohol and marijuana (cannabis) during treatment because the symptoms listed above may increase. Additionally, you should not drive or operate heavy machinery during treatment until you can do it safely.

Inform your healthcare provider if you are pregnant or want to become pregnant before using Aldactone 25 mg. Otherwise, it may harm you and your unborn baby. In addition, talk with a physician before breastfeeding because Spironolactone passes into breast milk.


  • It is advised to store this product at room temperature (below 30 C or 86 F degrees) and away from moisture and direct sunlight. Therefore, you should not keep Aldactone 25 mg in the bathroom.
  • Keep away Spironolactone from the reach of children and pets because it also may be harmful to them.

Additional information

Active Ingredient



RPG Life Sciences Ltd.


15 tabs/blister




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