Abamune-L (Abacavir/Lamivudine) is used to treat HIV (human immunodeficiency virus) infection in adults, adolescents and children weighing at least 25 kg.

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What is Abamune-L Abacavir/Lamivudine and what is it used for?

Abamune-L contains two drugs used to treat HIV infection: abacavir and lamivudine. These drugs belong to a group of antiretroviral medicines called nucleoside analogue reverse transcriptase inhibitors (NRTIs).

Abamune-L Abacavir/Lamivudine can not completely cure your HIV infection; It lowers viral load in your body and keeps it low. It also boosts the CD4 cell count in your blood. CD4 cells are a type of white blood cells that help your body fight infections.

Not everyone responds immediately to treatment with Abamune-L. Your doctor will monitor the effectiveness of your treatment.

What should you watch out for before taking Abamune-L Abacavir/Lamivudine?

Abamune-L should not be taken,

  • if you are allergic (hypersensitive) to Abamune (or any other medicine containing abacavir), to lamivudine or any of the substances listed in section 6. ingredients of this medicine.
    Read all information on hypersensitivity reactions in Section 4. carefully.

Talk to your doctor if you think you are. Do not take Abamune-L.

Warnings and Precautions

Some people taking Abamune-L Abacavir/Lamivudine or other combination HIV therapies are at increased risk for serious side effects. You should be aware of these additional risks:

  • if you have moderate or severe liver disease
  • if you have ever had liver disease, including hepatitis B or C (if you have a hepatitis B infection, do not stop taking Abamune-L Abacavir/Lamivudine without consulting your doctor, as you may experience a relapse of hepatitis)
  • if you are severely overweight (especially if you are female)
  • if you have kidney problems

If any of these conditions apply to you, talk to your doctor before taking Abamune-L. In these cases, additional check-ups, including blood tests, may be required while you are taking your medicine. See section 4. for more information.

How to take Abamune-L Abacavir/Lamivudine?

Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are not sure.

The recommended dose of Abamune-L Abacavir/Lamivudine for adults, adolescents and children weighing 25 kg or above is one tablet once daily.
Take the tablets whole with water. Abamune-L Abacavir/Lamivudine can be taken with or without a meal.

Stay in regular contact with your doctor Abamune-L Abacavir/Lamivudine helps to keep your illness under control. It is necessary that you take Abamune-L Abacavir/Lamivudine every day to prevent worsening of your condition. Other infections or diseases related to HIV infection may still occur.
Stay in regular contact with your doctor and do not stop taking Abamune-L Abacavir/Lamivudine without first consulting your doctor.

If you take more Abamune-L Abacavir/Lamivudine than you should
If you accidentally take too much Abamune-L Abacavir/Lamivudine, tell your doctor or pharmacist or contact the nearest emergency department for further advice.

If you forget to take Abamune-L Abacavir/Lamivudine
If you forget to take a dose, take it as soon as you remember. Then continue taking as before. Do not take in twice the amount if you forget to take the previous dose.
It is important to take Abamune-L Abacavir/Lamivudine regularly as an irregular dose may increase the risk of hypersensitivity.

If you stop taking Abamune-L Abacavir/Lamivudine
If you have stopped taking Abamune-L Abacavir/Lamivudine for some reason – especially if you think you have side effects or another condition:
See your doctor before taking it again. Your doctor will check if your symptoms are due to a hypersensitivity reaction. If your doctor thinks there may be a connection, he will tell you never to take Abamune-L Abacavir/Lamivudine or any other medicine containing abacavir (eg Trizivir or Ziagen) again. It is important that you follow this instruction.
If your doctor has instructed you to take Abamune-L Abacavir/Lamivudine again, you may be asked to take your first doses in an institution that will provide you with prompt medical attention if necessary.

What side effects are possible?

During HIV therapy, weight gain and blood lipid and blood glucose levels may increase. This is partly due to improved health and lifestyle; sometimes with the HIV medicines themselves. Your doctor will check you for these changes.

Like all medicines, this medicine can cause side effects, although not everybody gets them.
If you are being treated for HIV infection, it is not always possible to tell with certainty whether a symptom that has occurred is a side effect caused by Abamune-L Abacavir/Lamivudine or other medicines taken or caused by the HIV disease itself. For this reason, it is very important that you inform your doctor about any changes in your health.
Even patients who do not have the HLA-B * 5701 gene can still develop a hypersensitivity reaction (a serious allergic reaction). This reaction is described in this leaflet in the “Hypersensitivity Reactions” section.

It is very important that you read and understand the information about this serious reaction.

In addition to the side effects listed below for Abamune-L Abacavir/Lamivudine, other comorbidities may also develop with HIV combination therapy.
It is important that you read the information below in this section under “Other Possible Side Effects of HIV Combination Therapy”.

How to store Abamune-L Abacavir/Lamivudine?

Keep this medicine out of the sight and reach of children.

You must stop using this medicine after the expiry date which is stated on the carton and the blister pack after “Use by” The expiry date is the last day of the given month.

Do not dispose drugs in the wastewater or household waste. Ask your pharmacist how to dispose of the medicine when you stop using it. You help to protect our environment.

Contents of the pack and further information

What Abamune-L Abacavir/Lamivudine contains:

The active substances are abacavir and lamivudine.
Each tablet contains 600 mg abacavir and 300 mg lamivudine.
The other ingredients are:

  • Tablet Core: Microcrystalline Cellulose, Hyprolose, Carboxymethyl Starch Sodium (Type A) (Ph.Eur.) And Magnesium Stearate (Ph.Eur.).
  • Film coating: hypromellose, macrogol 4000, titanium dioxide, polysorbate 80, ferric hydroxide oxide x H2O and ferric oxide.

What Abamune-L Abacavir/Lamivudine looks like and contents of the pack

Abamune-L Abacavir/Lamivudine film-coated tablets are orange, oblong (approximately 20.5 mm x 9 mm) and biconvex, stamped 600 on one side and embossed 300 on the other side.

Abamune-L Abacavir/Lamivudine is available in packs containing 10, 30 and 90 film-coated tablets in blister packs or 10×1, 30×1 and 90×1 film-coated tablets in perforated single-dose blister packs.

Not all pack sizes may be marketed.

Additional information

Active Ingredient

Abacavir, Lamivudine

Brand Equivalent




Pharmaceutical Form

30 tabs/bottle


300 mg, 600 mg


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